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See:
Description
| Class Summary | |
|---|---|
| ApproxGCHap | This program finds approximations to the maximum likelihood estimates of haplotype frequencies from a sample of genotyped individuals. |
| CheckErrors | This program finds the posterior probabilities of errors for genotypes on individuals in pedigrees given a set of observed genotypes and the pedigree structure. |
| CheckFormat | This program reads in LINKAGE parameter and pedigree files, checks that they are readable and then outputs the checked files. |
| CheckParameters | This program reads in a LINKAGE parameter, checks that it is correctly foratted and then outputs the checked file. |
| CheckPedigree | This program reads in LINKAGE a pedigree file, and checks that the pedigree information is correctly formatted and self consistent. |
| CheckTriplets | This program checks a pedigree specified by a list of triplets for self consisency and completeness. |
| cMorgansToTheta | This program reads in a LINKAGE parameter file assuming that the distances between the loci are specified as cMorgans. |
| DownCodeAlleles | This program reduces the number of alleles in the models for the given genetic loci to include only alleles that appear in the pedigree file plus, optionally, one catchall allele to represent the unseen alleles which has frequency equal to the total frequency of the original unseen alleles. |
| GCHap | This program finds maximum likelihood estimates of haplotype frequencies from a sample of genotyped individuals. |
| GeneCountAlleles | This program calculates maximum likelihood estimates of allele frequencies from genotypes observed in individuals related in pedigrees. |
| GeneDrop | This program uses the multi locus gene drop method to simulate genotypes on a pedigree to match those in the input. |
| GeneDrops | This program uses the multi locus gene drop method to simulate genotypes on a pedigree to match those in the input. |
| GetPolymorphisms | This program selects from the input data the marker loci for which at least two alleles are observed. |
| GMCheck | This is the old name for the program CheckErrors. |
| HapGraph | This program estimates a graphical model for linkage disequilibrium or allelic associateion from genetic data. |
| HetCutOff | This program selects from the input data the marker loci for which the heterozygosity score is higher than a given threshold. |
| Heterozygosities | This program reads in a LINKAGE parameter, and outputs the heterozygosity measure for each locus. |
| HetLods | This program calculates two point hetlod scores on a grid of points. |
| HGS | This program calculates the runs of loci at which the selected individuals are all homozygous, but not necessarily for the same allele. |
| IntervalLD | This program estimates a interval graphed graphical model for linkage disequilibrium between genetic loci. |
| LinkageToFastPhase | Takes data from LINKAGE format parameter and pedigree files and prepares it for input into the FASTPHASE haplotyping program. |
| LinkageToPhase | Takes data from LINKAGE format parameter and pedigree files and prepares it for input into the PHASE haplotyping program. |
| MakeProbands | This programs marks inividuals in a pedigree file as being or not being probands. |
| MaxTwoPointLods | This program finds the maximum lod score for values of the recombination between 0 and 1 (not 0 and 0.5). |
| McLink | |
| McLinkLD | This program calculates linkage statistics while jointly estimating a model for linkage disequilibrium between the loci. |
| ObligateErrors | This program checks genotype data on pedigrees and indicates whether the data at any particular locus is inconsistent with Mendelian inheritance. |
| OnePoints | This program calculates the log likelihood for the data for each pedigree at each locus specified in the input. |
| SelectKindreds | This program selects a subset of kindreds from a LINKAGE pedigree file. |
| SelectLoci | This program selects a subset of loci from LINKAGE parameter and pedigree files. |
| SelectPedigrees | Another name for the SelectKindreds program. |
| SGS | This program calculates the runs of heterozygous sharing for a set of individuals in a pedigree. |
| SimHGS | This program performs multi locus gene drop simulations in order to assess the distribution of the length of regions of homozygosity, as calculated by HGS . |
| SimSGS | This program performs multi locus gene drop simulations in order to assess the distribution of the length of heterozygously shared genomic regions, as calculated by SGS . |
| TrimPed | This program removes individuals from the pedigree unless they have a minimum number of loci at least partially observed or they are ancestors of someone else that is observed. |
| TwoPointLods | This program calculates two point lod scores on a grid of points. |
| ViewGraph | This is and interactive graphical program for viewing and editing a graph. |
| ViewLinkPed | This is an interactive graphical program for viewing pedigree data. |
| ViewPed | This is an interactive graphical program for viewing pedigree data. |
| ZeroLoopPed | This program generates random zero loop pedigrees with specified numbers of marriages and individuals. |
This default "Unnamed" package contains all the top level programs. These are the only programs that a user needs to know about unless they are writing their own programs using the packages that underlies them.
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